The Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is responsible for the world's biggest public health crisis in the last 50 years. SARS-CoV2 has an important neurotropism causing a wide range of neuropsychiatric manifestations. SARS-CoV2 was identified in the brain and CSF of patients showing that direct and indirect viral mechanisms can contribute to the neuropsychiatric manifestations of this disease. Furthermore, evidence shows that cytokines released during viral infection in pregnancy or neonatal life and not exactly an immediate effect of the virus would underlie the emergence of neuropsychiatric alterations such as autism and schizophrenia, reinforcing the importance of the study of long-term COVID-19 and its consequences in our children. Thus, considering the vast number of recent cases of COVID-19 and the enormous expansion of this virus in Brazil, early identification of gestational issues of COVID-19 and understanding the long-term neuropsychiatric complications that may be associated with the virus is of paramount importance for the application of effective preventive/curative strategies. Therefore, the present study is critical because it makes it possible to provide answers and tools to questions that affect this generation and the next generation in the form of mental disorders.